3D-Bioplotter® Material Overview The 3D-Bioplotter® System is a suitable Rapid Prototyping Tool for processing a great variety of biomaterials within the process of Computer Aided Tissue Engineering from scaffolds 3D CAD model to the physical 3D scaffold with a designed and defined outer shape and an open inner structure. Tissue Engineering and Controlled Drug Release require 3D scaffolds with well defined external and internal structures. The 3D-Bioplotter® has the capacity of fabricating scaffolds using the widest range of materials of any singular Rapid Prototyping machine, from soft hydrogels over polymer melts up to hard ceramics and metals. Fabrication Method and Hardening Process Post-process sintering: Hydroxyapatite, TCP, Titanium Precipitation: Chitosan, Collagen 2-component system: Alginate, Fibrin, PU, Silicone Phase transition liquid - solid: Agar, Gelatine, PCL, PLGA, PLLA UV Curing: Acrylates, Silicones The EnvisionTEC 3D-Bioplotter® 3D printing technique may be described as the deposition of multiple materials in three dimensions using pressure. Materials range from a viscous paste to a liquid, and are inserted using syringes moving in three dimensions. Air pressure is applied to the syringe, which then deposits a strand of material for the length of movement and time the pressure is applied. Parallel strands are plotted in one layer. For the following layer, the direction of the strands is turned over the center of the object, creating a fine mesh with good mechanical properties and mathematically well-defined porosity. EnvisionTEC GmbH Brüsseler Straße 51 • D-45968 Gladbeck • Germany Phone +49 2043 9875-0 Fax +49 2043 9875-99 15162 S. Commerce Dr. Dearborn, MI 48120 • USA Phone +1-313-436-4300 Fax +1-313-436-4303 www.envisiontec.com [email protected] Version MK-MTS-Bioplotter-V3-DR-EN EnvisionTEC, Inc.
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