impact A Sensitive Subject: Update on our Current Understanding of Gluten Sensitivity

impact
FALL 2010
A Sensitive Subject: Update on our Current
Understanding of Gluten Sensitivity
Sonia S. Kupfer, MD
“Gluten gives me diarrhea and bloating but my doctor
tested me for celiac disease and I am negative. Do I
have gluten sensitivity?” This is a common question we
hear in the Celiac Center, and one that can be difficult
to answer.
The problem lies in the fact that we don’t have
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Moreover, there is overlap with celiac disease
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or altered immune response when exposed to
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such as chronic diarrhea and abdominal
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in whom celiac disease has been excluded
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for further study of clinical manifestations
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Sonia S. Kupfer, MD
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without other features that are classically
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these responses appeared to be independent
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these and other studies will help to further
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celiac disease has been ruled out that they
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Stefano Guandalini, M.D.
Founder and Medical Director
University of Chicago Comer Children’s Hospital
Section Chief, Pediatric Gastroenterology,
Hepatology and Nutrition
Advisory Board
Wendy Weil, D.P.M., Chairperson
Cindy Day Erwin, Vice Chairperson
Stuart Gordon, Treasurer
Bonnie Sclamberg, Membership
Lara Field, M.S., R.D., Secretary
Tripti Kasal, Immediate Past Chairperson
Lisa Aiken
Susan Blumenfeld
Carin Foote
Jessica Foote
Gary Frank
Joyce Frank
Deborah Gordon
Bana Jabri, M.D., Ph.D.
Kim Koeller
Sonia Kupfer, M.D.
Laura J. Lazarczyk
Judy Petrungaro
Gail Pierce
Lori Rowell, MS, RD, LDN
Carol Semrad, M.D.
Sueson Vess
Peggy Wagener
Elizabeth Wall, MS, RD, CNSC, LDN
Jonathan S. Yaffe, CPA
STAFF
Carol M. Shilson
Executive Director
Ronit Rose
Program Manager
NurAlima Grandison
Research Coordinator
The University of Chicago Celiac Disease Center
is dedicated to raising awareness and diagnosis
rates and meeting the critical needs of people
affected by celiac disease nationwide through
education, research and advocacy.
The contents of this newsletter are not
intended to diagnose or recommend treatment
for celiac disease. Please consult your healthcare
provider with questions about your condition.
For more information about The University of
Chicago Celiac Disease Center, please contact
our office:
The University of Chicago Celiac Disease Center
5841 S. Maryland Ave., MC 4069
Chicago, IL 60637
Ph.: (773) 702-7593 Fax: (773) 702-0666
[email protected] www.CeliacDisease.net
Figure1. Gluten sensitivity falls between irritable bowel syndrome (IBS) and celiac disease (CD). Used
by permission of Nature Publishing Group(1)
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continued sensible research we’ll be better able
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REFERENCES:
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Between celiac disease and irritable
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send an email with your contact information to [email protected] We will contact you
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Celiac Center at the Port
Clinton Art Fair
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special opportunity, as well as all the volunteers who participated in
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Celiac Center boardmembers Bonnie Sclamberg, Susan Blumenfeld and
Gail Pierce braved sweltering weather to promote greater awareness of
celiac disease at the Port Clinton Art Fair in August.
Bowling and Bocce for Celiac Disease
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Dr. Guandalini focuses
intently on his bocce
game.
Help fund the cure: We still need your help to reach our goal.
If you‘d like to donate, please contact Carol M. Shilson at (773) 834-0166.
$2 MILLION
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The Celiac Disease database, created three
years ago by Drs. Guandalini, Semrad, and
Kahn, along with The University of Chicago
Celiac Disease Center, continues to expand.
The database, managed by Celiac Center
Research Coordinator NurAlima Grandison,
has three undergraduate research
assistants working on it to input the
collected data. We continue to enroll both
adult and pediatric patients on an on-going
basis. We expect to begin work on data
analysis this fall, and we hope to produce
several meaningful publications from this
work over the next few years.
The University of Chicago Celiac
Disease Center is also working with
other institutions on a study on the role
of breastfeeding in the timing of gluten
introduction and intestinal microbiome on
the development of celiac disease. We are
serving as one of the regional directors for
this study and are currently coordinating
study initiation at the ten sites we are
overseeing both in the United States and
Canada.
Our study on immunological mechanisms
of celiac disease is beginning to yield
fascinating findings based on Dr. Jabri’s
research with human tissue from biopsy
tissue collected from patients for this
study. A publication regarding the findings
is currently under review by a major
scientific journal.
The Eating Behavior Study mentioned
in the Summer 2010 newsletter continues
to look for more participants. For more
information on this or any of the other
studies mentioned above, please contact
NurAlima Grandison at (773) 702-3572 or
[email protected]
Upcoming Events
THE UNIVERSITY OF CHICAGO CELIAC
DISEASE CENTER HAS LOTS OF EVENTS COMING UP OVER THE NEXT FEW MONTHS.
IN ORDER, THEY ARE:
October 9, 2010: Annual Celiac Disease Blood Screening and Q &A Panel. (See article
on page 2).
October 21-24, 2010: The University of Chicago Celiac Disease Center will be
participating in The North American Society for Pediatric Gastroenterology, Hepatology,
and Nutrition (NASPGHAN) annual meeting and postgraduate course this October 21st
– 24th in New Orleans, LA. NASPGHAN is the only professional society for pediatric
gastroenterologists in North America. The University of Chicago Celiac Disease Center
will be featured in the exhibit hall of the conference, and will provide information on our
innovative program to the largest gathering of pediatric gastroenterologists, hepatologists,
research scientists and physician nutritionists throughout the four-day conference.
Care Package
Partners
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November 5-8, 2010: The University of Chicago Celiac Disease Center will also be
participating in the Annual Food & Nutrition Conference & Expo, the showcase annual
meeting for the American Dietetic Association in Boston. This event allows us to meet
hundreds of dietitians all over the world. It’s a great opportunity to let them know who we
are and that we can be a resource for their newly diagnosed patients, no matter where they
live. It also gives us the opportunity to emphasize the importance of the gluten-free diet
for diagnosed celiac patients, and to form vitally important relationships and partnerships
with companies producing gluten-free food.
November 8-12, 2010: We are thrilled to announce that we will be partnering with
Wildfire Restaurants for a week of Gluten Free dining to benefit The University of Chicago
Celiac Disease Center! Each night of the week (Monday-Friday), a different Chicago-area
Wildfire will host a gluten-free dinner. Tickets will cost $75 each, including a $25 to the
Celiac Center. The dates and locations are:
Monday, Nov. 8:
Tuesday, Nov. 9:
Wednesday, Nov. 10:
Thursday, Nov. 11:
Friday, Nov. 12:
Chicago
Oakbrook
Glenview
Schaumburg
Lincolnshire
Enjoy a four-course gourmet feast with wine pairings. Reservations
are required. Please call Shannon Ryan at 312-787-9000 for
reservations.
December 2-3, 2010: The 5th Annual Preceptorship Program in Celiac Disease. We are
still accepting applications from physicians of all specialties and dietitians for the 2010
Preceptorship Program. This is a two-day intensive course that includes clinic observation,
lecture, Q & A and case presentation with the various experts in celiac disease at the
University of Chicago.
Bakery on Main
Betty Crocker
Bhuja
Bob’s Red Mill
Cabot Creamery
Chebe
Enjoy Life Foods
Green Giant
May 6, 2011: The annual Spring Flours™ Event at the Swissôtel in downtown Chicago.
As always, a fabulous line-up of Chicago’s finest gourmet gluten-free food, and a fun silent
and live auction.
Jones Sausage
Kettle Cuisine
For more information, go to: www.CeliacDisease.net/programs-&-events.
L & J Popcorn
Lärabars
Mary’s Gone Crackers
Namaste
Nature Valley
Pamela’s
Peanut Butter & Co.
Progresso
Protein Plus Peanut Flour
Rice Chex
San-J
Schar
Mr. Krispers and Crunchmaster
Udi’s
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Send good wishes for the Holidays and New Year and
help raise funds for our Center.
Custom greeting cards are now available for purchase
at: http://morethancards.com
Please click on our logo to make sure a portion of proceeds comes to our Center. Please
visit our website for more information at:www.CeliacDisease.net
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