BIOGRAPHICAL SKETCH NAME POSITION TITLE Krook, Anna Christina Professor EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) INSTITUTION AND LOCATION University of East Anglia, Norwich, England Queens University, Kingston, ON, Canada Cambridge University, Cambridge, England Karolinska Institutet, Stockholm, Sweden. Karolinska Institutet, Stockholm, Sweden Karolinska Institutet, Stockholm, Sweden DEGREE (if applicable) YEAR(s) B.Sc (1st Class Hons) M.Sc. Ph.D Post-doc. Docent Professor 1988 1991 1996 1997 2002 2010 FIELD OF STUDY Biological Science/Genetics Pathology Clinical Medicine Clinical Physiology Cell Physiology Integrative physiology and diabetes Positions and Employment 2010-to date Professor, Group leader, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden 2006-2012 Senior research position (VR forskare) from Swedish Research Council, “Diabetes” 2002-2010 Associate Professor in Cell Physiology, Department of Physiology and Pharmacology Karolinska Institutet, Stockholm, Sweden 1998-2001 Assistant Professor in Physiology, Department of Surgical Sciences, Division of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden 1996-1997 Post-doctoral fellow, Department of Surgical Sciences, Division of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden 1992-1996 Graduate Student (Elmore Studentship), Departments of Medicine and Clinical Biochemistry, Cambridge University, England 1991-1992 Research Assistant, Cambridge University, Department of Clinical Biochemistry, Addenbrookes Hospital, Cambridge, England 1989-1991 Graduate Student for M.Sc. studies; Cancer Research Laboratories, Department of Pathology, Queens University, Ontario, Canada Adjunct professorships 2009-to date Albert Einstein School of Medicine, New York, USA Member of editorial boards and commissions of trust 2014-to date 2013-to date 2009-to date 2008-2012 2007-2011 2003-2007 Short CV Scientific Advisory Board , German Institute of Human Nutrition, Potsdam, Associate Editor Diabetes, 2013-to date Scientific Secretary, Swedish Diabetes Association Associate Editor Diabetologia, Editorial Board American Journal of Physiology, Endocrinology and Metabolism Editorial Board Journal of Endocrinology 2014 Academic committees 2012-to date Karolinska Institutet representative 4D Diabetes project 2005-to date Member of steering group (ledningsgruppen) at Department of Physiology and Pharmacology, Karolinska Institutet 2004 Member of working group on resource allocation (KI05; Karolinska Institutet) 2002-2008 Member of Karolinska Institutet associate professor review committee (Docenturnämnden) Research evaluation 2014-to date Novo Nordisk Foundation Nordic Research committee 2013 Reviewer SSF – Future research leaders (Framtidens forskningsledare, LV2) 2007-to date Scientific Secretary of Swedish Diabetes Association Scientific Council from 2012 Member of Swedish research council grant evaluation for Danish applications 2012 Abstract reviewer for American Diabetes Association 2012 Review panel of the Danish Council for Independent Research, FSS Metabolism Panel 2010-2011 Chairperson of Swedish research Council Grant evaluation panel MB2 2007-2012 Member of grant review board, Karolinska Institutet funds 2007-2008 Chairperson of Swedish research Council Grant evaluation panel MB2 2010 Member of grant review board, European Foundation for the Study of Diabetes, 2006 Chairperson of Finnish Academy evaluation of postdoctoral grants 2005 Member of Swedish research Council “Cell biology 2” grant evaluation 2005-2007 Chairperson for evaluation of AFA and Hageléns post doc-stipends, Karolinska Institutet, 2004 Evaluator of Shizu Matsumuras donation/ Karolinska Institutet grants 2004 External reviewer on grant applications for British medical research council 2004 External reviewer on grant applications for Austrian FWF Der Wissenschaftfonds Organisation of international scientific meetings 2014 Programme Committee, Scandinavian Physiological Society 2012 Programme Committee, European Association of Diabetes (EASD) annual meeting 2011 Programme Committee, European Association of Diabetes (EASD) annual meeting Five selected publications: 1. R Barrès, ME Osler, J Yan, A Rune, T Fritz, K Caidahl, A Krook, JR Zierath (2009). Non-CpG Methylation of the PGC-1a Promoter through DNMT3B Controls Mitochondrial Density. Cell Metab 10:189-98 2. A Shemyakin, F Salehzadeh, D Esteves Duque-Guimaraes, F Böhm, E Rullman, T Gustafsson, J Pernow, A Krook (2011). Endothelin-1 reduces glucose uptake in human skeletal muscle in vivo and in vitro. Diabetes 60:2061-2067 3. LQ Jiang*, DE Duque-Guimaraes * UF Machado, JR Zierath, A Krook (2013) Altered response of skeletal muscle to IL-6 in Type 2 diabetic patients. Diabetes 62:355-61 4. LQ Jiang, N Franck, B Egan, RJO Sjögren, M Katayama, D Duque-Guimaraes, P Arner, JR Zierath, A Krook (2013) Autocrine role of interleukin-13 on skeletal muscle glucose metabolism in Type 2 diabetic patients involves microRNA let-7 Am J Physiol 305:E1359-66 5. Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression. LZ Agudelo, T Femenía, F Orhan, M Porsmyr-Palmertz, M Goiny, V Martinez-Redondo, JC Correia, M Izadi, M Bhat, I Schuppe-Koistinen, AT Pettersson, DM Ferreira, A Krook, R Barres, JR Zierath, S Erhardt, M Lindskog, JL Ruas (2014). Cell. 159:33-45.
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