10:30 Fri 28 Data Blitz Session IV

NECTAR 2014 Data Blitz Presentations
10:30 Thu 27th Data Blitz Session I
10:30 Fri 28th Data Blitz Session IV
Ms. Stefanie Seiler, University Hospital & University of Bern
Assessments of new strategies to improve yield of dopaminergic neurons in
vitro: Effects of Nogo-receptor 1 antagonization and NT4/5
Dr. Jonathan Niclis, University of Melbourne
Improved ventral midbrain differentiation of human pluripotent stem cells
for cellular replacement therapy.
Mr. Christopher Turner, Florey Institute of Neuroscience
Immune suppression strategies for long-term survival of human stem cell
grafts in the rodent brain.
Ms. Jessica Kauhausen, University of Melbourne
The importance of striatal contact for the survival and integration of
neural transplants in Parkinsonian mice.
Mr. Tiago Cardoso, Lund University
Synaptic integration of transplanted human embryonic stem cell derived
neurons in the adult rat brain.
Dr. Agnete Kirkeby, Lund University
Reconstruction of midbrain dopamine pathways in the adult rat brain
using dopamine neurons derived from human embryonic stem cells.
13:00 Thu 27th Data Blitz Session II
Ms. Síle Griffin, Keele University
Accelerated and efficient neuronal differentiation of Sox1GFP mouse
embryonic stem cells in vitro using nicotinamide.
Dr. Sophie Rowlands, Cardiff University
Can manipulation of differentiation conditions eliminate proliferative cells
from a population of ES cell‐derived forebrain cells?
Mr. David Harrison, Cardiff University
Primary foetal cell suspensions, tissue pieces and donor age: A comparison
of morphology in striatal mouse grafts.
Dr. Mariah Lelos, Cardiff University
Comparison of rat and human whole ganglionic eminance fetal tissue
grafts on behaviour and graft maturation.
Dr. Victoria Roberton, Cardiff University
Characterising the development of human WGE grafts.
Ms. Emma Yhnell, Cardiff University
A longitudinal behavioural characterisation of the HdhQ111 mouse
model of Huntington’s disease.
15:30 Thu 27th Data Blitz Session III
Ms. Rachel Ronan, NUI Galway
A collagen-based multimodal delivery system provides therapeutic factors
and physical support for treatment of spinal cord injury in the rat.
Dr. Ting-Yi Wang, Florey Institute of Neuroscience
Bioengineered scaffolds enhance the functional integration of transplanted
human embryonic stem cell-derived cortical progenitors in an animal
model of focal ischemia.
Mr. Fahad Somaa, University of Melbourne
Long-lasting motor improvement following neural transplantation in
athymic rats with ischemic brain injury.
Dr. Ike de la Pena, University of South Florida
Granulocyte colony-stimulating factor attenuates delayed tPA-induced
hemorrhagic transformation in ischemic stroke rats by enhancing
angiogenesis and vasculogenesis.
Prof. Hans Rudolf Widmer, University of Bern
The secretome of endothelial progenitor cells supports brain microvascular
cells viability.
Mr. Simon Rodier, University of Cambridge
Functional role of intermediate filaments in oligodendrocyte lineage cells
and CNS remyelination.
Ms. Lucy Collins, University of Cambridge
Relationship between cognitive status in Gaucher related Parkinson’s
disease and lysosome function in patient fibroblasts.
Mr. Martin Madill, NUI Galway
Impaired autophagy in Amyotrophic Lateral Sclerosis patient
Dr. Karolina Pircs, Lund University
Revealing the influence of autophagy on miRNA function in different
models of Parkinson’s and Huntington's disease.
Ms. Josephine Malmevik, Lund University
Global dopaminergic microRNA changes in LRRK2(R1441G)
transgenic mice.
Dr. Zinovia Kefalopoulou, University College London
Long-term outcomes of STN - DBS: A benchmark for novel biological
treatments for Parkinson’s disease?
Ms. Ruth Concannon, NUI Galway
Differential upregulation of the cannabinoid CB2 receptor in neurotoxic
and inflammation-driven rat models of Parkinson's disease.
13:00 Fri 28th Data Blitz Session V
Dr. Shane Hegarty, University College Cork
Neurotrophic effects of GDF5 and BMP2 on cultured midbrain
dopaminergic neurons are mediated by the canonical Smad 1/5/8
signalling pathway.
Mr. Thomas Padel, Lund University
Platelet-derived growth factor BB restores the striato-nigral dopaminergic
system and its associated behaviour in a 6-hydroxydopamine mouse
model of Parkinson’s disease: involvement of pericytes.
Mr. Osama Elabi, Cardiff University
The impact of Ghrelin on the survival and efficacy of transplanted
allogenic ventral mesencephalon in a rat model of Parkinson’s disease.
Ms. Deirdre Hoban, NUI Galway
Assessment of the neurotrophic effects exerted by GDNF following
delivery of neurotrophin-secreting stem cells to the rat brain in the
lipopolysaccharide model of Parkinson’s disease.
Dr. Katie Hall, University of Cambridge
Bilateral striatal AAV5-GDNF treatment fails to ameliorate
behavioural deficits in R6/1 Huntington’s disease model mice.
Ms. Juhi Samal, NUI Galway
Fibrin-based microsphere reservoirs for delivery of neurotrophic factors.
Mr. Andre Toulouse, University College Cork
TNFa inhibits survival of midbrain neural precursor cells: an antiinflammatory role for Nurr1?
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