10th Annual Meeting of the Collaborative Group of the Americas on Inherited Colorectal Cancer November 9-10, 2006 DoubleTree Hotel Nashville 315 4th Avenue North Nashville, Tennessee Photo: Barry M. Winiker Preceding The National Society of Genetic Counselors (NSGC) meeting held at the Gaylord Opryland Resort. 10th Annual Meeting of the Collaborative Group of the Americas on Inherited Colorectal Cancer Goal This program was developed in recognition of the need for clinicians and scientists to keep abreast of current information in hereditary colorectal cancer research – including its implications in the prevention, diagnosis and treatment of patients with colorectal cancer. Increasing emphasis will be on awareness of and participation in development of clinical and translational trials. Educational Objectives (per Accreditation Council for Continuing Medical Education guidelines) After attending the conference, participants should be able to • review the molecular genetics of inherited colorectal cancer; • describe clinical features of common inherited colorectal cancer syndromes; • describe emerging research in hereditary colorectal cancer, including clinical, basic science, and psychosocial issues; • review chemoprevention treatment options for inherited colorectal cancer; • identify and resolve difficult case management issues in the treatment of hereditary colorectal cancer; • discuss the role of genetic counseling and hereditary colorectal cancer registries in providing patient education and promotion of interaction between patients and researchers. Learning Objectives (per American Board of Genetic Counselors’ guidelines) • Appreciate the ethical, legal, and psychosocial issues unique to hereditary colon cancer risk identification, management, and documentation. • Increase participants’ understanding of new screening, surgical, and research options available to their high risk patients. • Examine the impact of genetic evaluation, genetic counseling, and genetic testing on clinical care of individuals and families. Target Audience This conference will be beneficial to colorectal surgeons, medical oncologists, gastroenterologists, researchers, geneticists, nurses, colorectal cancer registry coordinators, genetic counselors, and psychologists involved in hereditary colorectal cancers. Educational Methods Lectures - Question and Answer Sessions - Panel Discussions - Case Presentations Exhibit Program Evaluation A course evaluation form will provide participants with the opportunity to review each session and speaker, to identify future educational needs, and to comment on any perceived commercial bias in the presentations. Accreditation/Credit Designation This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through this joint sponsorship of The University of Texas M. D. Anderson Cancer Center and The Collaborative Group of the Americas on Inherited Colorectal Cancer. The University of Texas M. D. Anderson Cancer Center is accredited by the ACCME to provide continuing medical education for physicians. The University of Texas M. D. Anderson Cancer Center designates this educational activity for a maximum of 11.75 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity. American Board of Genetic Counselors The event is co-sponsored by the American Counseling Association (ACA). ACA is approved by the National Board for Certified Counselors (NBCC) to offer up to 13.0 contact clock hours of continuing education credit. ACA adheres to NBCC continuing education guidelines. NBCC approved contact hours will be provided by ACA. ACA offers 10 contact clock hours for every (1) continuing education unit, as approved by the American Board of Genetic Counseling. The credits offered are Category 1 CEUs. Call for Abstracts Participants are encouraged to submit abstracts regarding clinical, basic science, and psychosocial aspects of hereditary colorectal cancer. We are interested in abstracts for both established projects with data to share and newly started projects. Our goal is to provide a comprehensive update on the status of clinical research and to stimulate collaborations, recruitment of subjects, and ideas for the development of other studies. Abstracts will only be accepted electronically and should be submitted to Larry Rusin, MD, CGA-ICC Vice President, at [email protected] The deadline for submission of abstracts is September 8, 2006. Acceptance of abstracts will be acknowledged by e-mail. Authors will be notified by October 6, 2006. All communication will be with the submitting author only. Limit abstracts to one page, typed in 12 point Times New Roman font, single-spaced with one-inch margins and left justified. Organize the abstract into Background, Methods, Results, and Conclusions. Define all abbreviations and provide three keywords describing the nature and content of the abstract. Please include the name of the conference, title of your presentation, full names of all authors, highest degree, institutional affiliation, and full address at the top of the abstract. Also, please indicate the presenting author by underlining the appropriate name. Abstracts will be selected for poster/oral presentations based on scientific merit and content quality. PROGRAM Wednesday, November 8, 2006 2:00 - 6:00 pm Registration/Poster Setup Thursday, November 9, 2006 7:30 am Registration/Continental Breakfast 8:25 Welcome Miguel A. Rodriguez-Bigas, MD Session: Who and How Do We Select for Mutational Testing for HNPCC? 8:30 Identifying Patients with Lynch Syndrome Heather Hampel, MS, CGC 8:45 Lab Diagnosis of Lynch Syndrome Russell R. Broaddus, MD, PhD 9:00 Lemuel Herrera Memorial Lecture Lynch Syndrome and Familial Colorectal Cancer Type X Noralane M. Lindor, MD 9:30 Panel Discussion 10:00 Break Session: Family History Documentation and Evaluation 10:30 Strategies To Obtain an Accurate Family History Janet Shenal 10:45 Applying Family History Information to the Genetic Evaluation Thuy Vu, MS, CGC 11:00 Networking/Discussion Angela Schwab, MS, CGC - Moderator Noon Box Lunch Pickup 12:30 pm Working Groups (each concurrent session limited to 40 participants) Resources for Patient and the Public and CGA Patient ID Tools Lori Aro; Erin R. Dola, MS, CGC; Anna Leininger, MS, CGC; Ellen McGannon, BSW Rare Tumors in HNPCC/Lynch Syndrome Scott Kuwada, MD and Katrina Lowstuter, MS, CGC Polyposis Syndromes: Classifications and Genetic Factors Marc Greenblatt, MD FAP Chemoprevention Patrick M. Lynch, MD, JD 1:30 Clinical Science Abstract Oral Presentations James Church, MD - Moderator 2:30 Invited Lecture: Dermatologic Findings in Hereditary Colon Cancer Syndromes Marcus Bosenberg, MD, PhD 3:00 Break 3:30 Challenging Cases 4:45 Adjourn 4:50 Poster Session/Reception 6:30 pm Dinner Lifetime Achievement Award “Growing Up With Henry Lynch” Patrick M. Lynch, MD, JD Friday, November 10, 2006 7:30 am Registration/Continental Breakfast Session: Diagnostic Challenges in Polyposis 8:30 MYH Missense Variants Sheila S. David, MD 8:45 Variants of Uncertain Significance Marc Greenblatt, MD 9:00 Prevalence of APC, MYH and HNPCC Mutations Based on Polyp Number Sapna Syngal, MD, PhD PROGRAM 9:15 Hamartomatous Polyposis Kevin Zbuk, MD 9:45 Panel Discussion 10:15 Break 10:45 Basic Science Abstract Presentations 11:45 Annual CGA Debate: Oligopolyposis: Colectomy vs. Surveillance Arguing for Colectomy: Lawrence Rusin, MD Arguing for Surveillance: Patrick M. Lynch, MD, JD 12:30 pm Business Meeting/Election/Buffet Lunch Session: Updates on Psychosocial Research in Hereditary Colon Cancer 1:30 Risk Perception/Communication Suzanne O’Neil, MA, MS, PhD 1:55 Educating Primary Care Clinicians Elena Stoffel, MD, MHP 2:20 Panel Discussion Session ends 2:45 Presidential Address and Best Abstract Awards Miguel A. Rodriguez-Bigas, MD 3:00 Break 3:15 Working Groups (each concurrent session limited to 40 participants) Colon Stem Cells/Pathology Bruce Boman, MD Chemoprevention of Hamartomatous Polyposis Syndromes Scott Kuwada, MD Psychosocial Research/Working With Children Susan K. Peterson, PhD, MPH and Wendy Kohlmann, MS, CGC Desmoid Working Group James Church, MD 5:00 Adjourn 6:00 pm Transportation provided to Gaylord Opryland Resort for those attending the National Society of Genetic Counselorss Meeting. Organizing Committee Miguel A. Rodriguez-Bigas, MD, Chair M. D. Anderson Houston, Texas Susan K. Peterson, PhD, MPH M. D. Anderson Houston, Texas James Church, MD The Cleveland Clinic Foundation Cleveland, Ohio Lawrence Rusin, MD Lahey Clinic Medical Center Burlington, Massachusetts Marc Greenblatt, MD University of Vermont Burlington, Vermont Angela Schwab, MS, CGC Huntsman Cancer Institute Salt Lake City, Utah Anna Leininger, MS, CGC Minnesota Colorectal Cancer Initiative Minneapolis, Minnesota Thuy M. Vu, MS, CGC M. D. Anderson Houston, Texas Katrina Lowstuter, MS, CGC City of Hope Duarte, California Jennifer Anderson M. D. Anderson Houston, Texas Patrick M. Lynch, MD, JD M. D. Anderson Houston, Texas Sharon D. Jackson M. D. Anderson Houston, Texas Ellen McGannon, BSW The Cleveland Clinic Foundation Cleveland, Ohio Joan Schauer, CMP M. D. Anderson Houston, Texas Bobbi J. McGivern, MS, CGC M. D. Anderson Houston, Texas Faculty Lori Aro Myriad Genetic Laboratories, Inc. Salt Lake City, Utah Katrina Lowstuter, MS, CGC City of Hope Duarte, California Marcus Bosenberg, MD, PhD University of Vermont Burlington, Vermont Patrick M. Lynch, MD, JD M. D. Anderson Houston, Texas Bruce Boman, MD Thomas Jefferson University Philadelphia, Pennsylvania Ellen McGannon, BSW The Cleveland Clinic Foundation Cleveland, Ohio Russell R. Broaddus, MD, PhD M. D. Anderson Houston, Texas Suzanne O’Neil, MA, MS, PhD Evanston Northwestern Health Care Evanston, Illinois James Church, MD The Cleveland Clinic Foundation Cleveland, Ohio Susan K. Peterson, PhD, MPH M. D. Anderson Houston, Texas Sheila S. David, MD University of Utah Salt Lake City, Utah Miguel A. Rodriguez-Bigas, MD M. D. Anderson Houston, Texas Erin R. Dola, MS, CGC St. Luke’s Regional Medical Center Boise, Idaho Lawrence Rusin, MD Lahey Clinic Medical Center Burlington, Massachusetts Marc Greenblatt, MD University of Vermont Burlington, Vermont Angela Schwab, MS, CGC Huntsman Cancer Institute Salt Lake City, Utah Heather Hampel, MS, CGC The Ohio State University Columbus, Ohio Janet Shenal The Cleveland Clinic Foundation Cleveland, Ohio Wendy Kohlmann, MS, CGC Huntsman Cancer Institute Salt Lake City, Utah Elena Stoffel, MD, MHP Brigham and Women’s Hospital Boston, Massachusetts Scott Kuwada, MD Huntsman Cancer Institute Salt Lake City, Utah Sapna Syngal, MD, PhD Dana-Farber Cancer Institute Boston, Massachusetts Anna Leininger, MS, CGC Minnesota Colorectal Cancer Initiative Minneapolis, Minnesota Thuy Vu, MS, CGC M. D. Anderson Houston, Texas Noralane M. Lindor, MD Mayo Clinic Rochester, Minnesota Kevin Zbuk, MD The Cleveland Clinic Foundation Cleveland, Ohio Registration Information On-site registration opens at 2:00 p.m. on Wednesday, November 8, 2006 in the Ballroom Foyer. The opening session of the conference will begin at 8:25 a.m. on Thursday, November 9, 2006, and the conference will adjourn at 5:00 p.m. on Friday, November 10, 2006. Advance registration is encouraged as space and materials are limited. Please see the registration form for applicable fees. The deadline for advance registration is Friday, October 27, 2006. There are four ways to register: • Mail to Department of CME/Conference Services, Unit 1381, The University of Texas M. D. Anderson Cancer Center, P.O. Box 301439, Houston, TX 77230-1439 • Fax to 713-794-1724 • E-mail to [email protected] • On-line at www.mdanderson.org/conferences We accept the following forms of payment: • Check (payable through U.S. banks only) • Money order • Credit cards (MasterCard, VISA, and American Express) • Cash (on-site registration only) A receipt and confirmation letter will be sent to you within ten working days of receipt of your registration. The conference registration fee includes the tuition, final program syllabus, continental breakfasts, lunches, breaks, and dinner. Refund/Cancellation Policy The registration fee, minus a $50 administrative handling fee, is refundable if a written request is received on or before October 27, 2006. No refunds will be granted after that date. The request for a registration refund must include the tax identification number of the company or institution if registration was paid by a company or institution check. Although no refunds will be granted after October 27, 2006, you may transfer your registration to a colleague. For additional information, contact CME/Conference Services at 713-792-2223 or toll free at 866-849-5866. The Department of CME/Conference Services reserves the right to cancel activities prior to the scheduled date, if low enrollment or other circumstances make it necessary. Each registrant will be notified either by mail, e-mail, or at the phone or fax numbers given on the registration form. In case of activity cancellation, the liability of the Department of CME/Conference Services is limited to the registration fee. CME/Conference Services will refund the full registration fee. The Department of CME/Conference Services reserves the right to limit the number of participants in a program and is not responsible for any expenses incurred by an individual whose registration is not confirmed and for whom space is not available. Special Assistance Contact the Department of CME/Conference Services at 713-792-2223 or toll free at 866-849-5866 if you have any special dietary or ADA accommodation needs. Accommodations • A block of rooms has been reserved for conference attendees at the DoubleTree Hotel Nashville, 315 4th Avenue, Nashville, TN. • Early hotel reservation is suggested. • The hotel phone number is 615-244-8200. • When you make reservations, be sure to mention the Collaborative Group of the Americas Conference to be assured of receiving the special meeting rate of $139.00 single or $149.00 double occupancy. Please add 14.25% (Tennessee) state and local taxes. • Reservations and deposits received after October 11, 2006, will be confirmed if space is available and at currently published hotel guest room rates. Air Travel The University of Texas M. D. Anderson Cancer Center has a program with Continental Airlines for discounted air travel. For discounts, call your travel professional or Continental's MeetingWorks toll free at 800-468-7022. Outside of the United States, please call your local Continental Airlines Reservation Office. Also, you may book online at www.continental.com. Enter your Z Code: ZKCS and Agreement Code: 3L23GL in the Offer Code Box when searching for flights. Lower fares may be available on the Internet or through your travel agency. Ground Transportation (prices subject to change) Taxicabs are available at an estimated cost of $25.00 from Nashville International Airport to the DoubleTree Hotel. The Gray Line Airport Express Shuttle services downtown Nashville hotels from Nashville International Airport. The cost is $12.00 one-way or $18.00 roundtrip. Service begins at 5:00 a.m. and runs until 11:00 p.m., with departures every 15-20 minutes. Reservations are not required for service from the airport. For further information check the website at www.graylinenashville.com. Please let us know what specific topics, issues or questions you wish to see addressed or emphasized in this activity. Fax or e-mail CME/Conference Services. All responses will be forwarded to the Program Chair for consideration. Collaborative Group of the Americas on Inherited Colorectal Cancer In 1995, the Collaborative Group of the Americas on Inherited Colorectal Cancer (CGAICC) was established to improve understanding of the basic science of inherited colorectal cancer and the clinical management of affected families. Its broad aims are to enhance the study of inherited colorectal cancer through • education of physicians, allied health-care professionals, patients and their families; • linkage to clinical and chemoprevention trials; • integration of molecular and clinical research at local and national levels; • resource for registry development and support of polyposis, inherited colorectal cancer, and cancer genetics. Included among CGA-ICC members are many of the most prestigious international colorectal cancer registries and clinics. Individual members include colorectal surgeons, medical oncologists, gastroenterologists, researchers, geneticists, nurses, colorectal cancer registry coordinators, genetic counselors, and psychologists. Typically, attendance at the annual meeting ranges from 150-200 individuals which serves to promote personal interactions and collaboration among the participants. Photo: Randy Piland Photo: Robin Hood Photo: Gary Layda REGISTRATION 10th Annual Meeting of the Collaborative Group of the Americas on Inherited Colorectal Cancer November 9-10, 2006 Please register by October 27, 2006 Last Name First Title (Mr./ Ms. ) MI Personal Title (II, Jr.) Degree State Zip Specialty Department Hospital Affiliation Address 1 Address 2 City Phone Cell Fax E-mail Registration $400.00 Physicians $250.00 Genetic Counselors & Coordinators $50.00 Late registration-after October 27, 2006 $40.00 for each additional dinner guest Total enclosed The University of Texas M. D. Anderson Cancer Center has implemented a process whereby everyone who is in a position to control the content of an educational activity must disclose all relevant financial relationships with any commercial interest that could potentially affect the information presented. M. D. Anderson also requires that all faculty disclose any unlabeled use or investigational use (not yet approved for any purpose) of pharmaceutical and medical device products. Specific disclosure will be made to the participants prior to the educational activity. Agendas are subject to change because we are always striving to improve the quality of your educational experience. M. D. Anderson may substitute faculty with comparable expertise on rare occasions necessitated by illness, scheduling conflicts, and so forth. Audiotaping or videotaping is prohibited.
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