Venue How to get there:

How to get there:
By train: take the Augsburg / Munich train to Günzburg
station. You can either take a taxi or walk 2.2 km.
Schloss Reisensburg
Bürgermeister-Johann-Müller-Str. 1
89312 Günzburg / Donau
Tel: +49 (0)8221 / 907-0
Michèle Zimmerman
Sekretariat SFB 1074
Universitätsklinik Ulm
Albert-Einstein-Allee 23
89081 Ulm
Tel: 0731-500-45523
Fax: 0731-500-45525
Email: [email protected]
By car: From Ulm (A8 direction München)
- Take the "Günzburg" exit and follow the signs for
- Stay on this road (B16) for about 3.3km. Turn left at the
junction "Günzburg Nord/Bahnhof".
- After about 250m turn left into "Ludwig-Heilmeyer-Str.",
signposted "Reisensburg".
- This road takes you into the village of Reisensburg. At the
end of that road, turn left and follow the road straight up the
- On the top of the hill, you will find free parking in front of
the gate of Schloss Reisensburg.
Günzburg is approx. 40km from Ulm.
Dear Ladies and Gentlemen,
We cordially invite you, principal investigators and scientific staff, to the second retreat
of our SFB 1074.
We look forward to an intensive discussion
and scientific interchange, as well as an
enjoyable day at Schloss Reisensburg!
Monday, February 10th, 2014
Arrival at Schloss Reisensburg
08:45 - 09:00
Welcoming remarks
Thomas Wirth
09:00 - 09:30
A1 Hartmut Geiger
Distinct DNA repair pathways in hematopoietic stem
cells – contribution to genetic instability and leukemia
09:30 - 10:00
Hartmut Döhner
10:00 - 10:30
A2 Hans Jörg Fehling
15:30 - 16:00 Martina Bach (Hassan Jumaa group)
"Role of PI3K signaling in CLL"
Z1 Hans Kestler, Christian Buske
16:30 - 17:00 B2 Daniel Mertens, Hartmut Döhner,
Coffee Break
11:00 - 11:30
A3 Franz Oswald
Notch signaling as a novel target of AML1/ ETO
A4 Christian Buske
Dissecting Lef1 function in leukemic stem cells
A7 Thomas Wirth
Role of EZH2 in B-lymphoid and myeloid leukemogenesis
12:30 - 13:30
Hartmut Geiger
13:30 - 14:00
A5 Arefeh Rouhi, Florian Kuchenbauer
(presenter will be Edith Schneider)
14:00 - 14:30
15:00 - 15:30 B1 Stephan Stilgenbauer
Telomere dysfunction in pathogenesis and clinical
course of CLL
16:00 - 16:30 Coffee break
10:30 - 11:00
12:00 - 12:30
Role of the hematopoiesis-specific Rho
GTPase RhoH in the development of B-cell
Dissecting hematopoietic defects in Mixed-LineageLeukemia-5-deficient mice and cell lines: towards a
molecular understanding of Mll5 function
Next generation sequencing facility - Parallel algorithms for robust clustering, classification, and visualization
11:30 - 12:00
14:30 - 15:00 A8 Peter Gierschik
Klaus-Michael Debatin
Stephan Stilgenbauer
Genomic and epigenetic mechanisms in CLL
17:00 - 17:30 B3 Konstanze Döhner, Lars Bullinger
Molecular and functional characterization of
cooperating events in acute myeloid leukemia with
NPM1 mutation
17:30 - 18:00 B4 Verena Gaidzik
Functional analysis of recurrent deletions of chromosomal band 3p14.1-p13 in acute myeloid leukemia
18:00 - 18:30 B6 Lüder-H. Meyer, Klaus-M. Debatin
The NOD/SCID/huALL xenotransplant model:
characterization and prognostic impact of distinct
engraftment properties (time to leukemia, TTL) of
primary ALL cells
Transcriptional and epigenetic regulation of microRNAs through MEIS1 in the pathogenesis of acute
myeloid leukemia
18:30 - 19:00 B7 Christian Beltinger
Attenuated oncolytic measles virus against ALL of
childhood: preclinical proof-of-principle and
molecular mechanisms
A6 Michaela Feuring-Buske, Vijay Rawat
19:00 - 19:15 Concluding remarks
VENTX: a novel regulator in human leukemias