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Department of Medicine, Jewish General Hospital
Publications January - December 2011
Agulnik, Jason
--Smith BM, Schwartzman K, Kovacina B, Taylor J, Kasymjanova G, Brandao G and Agulnik
J.S. Lung cancer histologies associated with emphysema on computed tomography. Lung
Cancer, 2011
Autexier, Chantal
--Brault, ME and Autexier C. Telomeric recombination is induced by dysfunctional telomeres.
Mol. Biol. Cell. 22:179-188, 2011
--Castor K, Mancini, J, Fakhoury J, Weill N, Kieltyka R, Englebienne P, Avakyan N, Langille A,
Mittermaier A, Autexier C, Moitessier N, Sleiman H.F. Platinum(II) phenanthroimidazoles for
targeting telomeric G-quadruplexes. ChemMedChem, 7:85-94, Epub November 2011
--Brault M.E. and Autexier C. ALTered telomeres in response to telomere dysfunction. Cell
Cycle, 10:3807-9, Epub November 2011
Baron, Murray
--Baron M, Hudson M, Steele R, Lo E, Canadian Scleroderma Research Group. Validation of the
UCLA scleroderma clinical trial gastrointestinal tract instrument version 2.0 for systemic
sclerosis. J Rheumatol 38:1925-30, 2011
--Fransen J, Johnson SR, van den Hoogen F, Baron M, Allanore Y, Carreira PE, Czirjak L,
Denton CP, Distler O, Furst DE, Gabrielli A, Herrick A, Inanc M, Kahaleh B, Kowal-Bielecka
O, Medsger TA, Jr., Mueller-Ladner U, Riemekasten G, Sierakowski S, Valentini G, Veale D,
Vonk MC, Walker U, Chung L, Clements PJ, Collier DH, Csuka ME, Jimenez S, Merkel PA,
Seibold JR, Silver R, Steen V, Tyndall A, Matucci-Cerinic M, Pope JE, Khanna D. Items for
developing revised classification criteria in systemic sclerosis: Results of a consensus exercise
with the acr/eular working committee for classification criteria in systemic sclerosis. Arthritis
Care Res (Hoboken) 64:358-67, 2011
--Galluccio F, Walker UA, Nihtyanova S, Moinzadeh P, Hunzelmann N, Krieg T, Steen V,
Baron M, Sampaio-Barros P, Kayser C, Nash P, Denton CP, Tyndall A, Muller-Ladner U,
Matucci-Cerinic M. Registries in systemic sclerosis: A worldwide experience. Rheumatology
(Oxford); 50:60-8, 2011
--Johnson SR, Fransen J, Khanna D, Baron M, van den Hoogen F, Medsger TA, Jr., Peschken
CA, Carreira PE, Riemekasten G, Tyndall A, Matucci-Cerinic M, Pope JE, Validation of
potential classification criteria for systemic sclerosis. Arthritis Care Res (Hoboken), 64:358-67,
2011
--Khimdas S, Harding S, Bonner A, Zummer B, Baron M, Pope J, Canadian Scleroderma
Research Group. Associations with digital ulcers in a large cohort of systemic sclerosis: Results
from the Canadian Scleroderma Research Group registry. Arthritis Care Res (Hoboken) 63:1429, 2011
--Looper K, Mustafa S, Zelkowitz P, Purden M, Baron M, McGill Early Arthritis Research
Group. History of depressive episodes as a risk factor for illness severity in early inflammatory
arthritis. J Psychosom Res 71:28-31, 2011
--Parapuram SK, Shi-wen X, Elliott C, Welch ID, Jones H, Baron M, Denton CP, Abraham DJ,
Leask A. Loss of PTEN expression by dermal fibroblasts causes skin fibrosis. J Invest Dermatol
131:1996-2003, 2011
--Sharif R, Fritzler MJ, Mayes MD, Gonzalez EB, McNearney TA, Draeger H, Baron M,
Canadian Scleroderma Research Group, Furst DE, Khanna DK, del Junco DJ, Molitor JA,
Schiopu E, Phillips K, Seibold JR, Silver RM, Simms RW, Group GS, Perry M, Rojo C, Charles
J, Zhou X, Agarwal SK, Reveille JD, Assassi S, Arnett FC. Anti-fibrillarin antibody in
africanamerican patients with systemic sclerosis: Immunogenetics, clinical features, and survival
analysis. J Rheumatol 38:1622-30, 2011
Bergman, Howard
--Richardson S, Karunananthan S, Bergman H. I May Be Frail But I Ain’t No Failure. Canadian
Geriatrics Journal, 14 (1):24-28, 2011
--Arsenault-Lapierre G, Whitehead V, Belleville S, Massoud F, Bergman H, Chertkow H. Mild
Cognitive Impairment (MCI) cognitive impairment subcategories depend on the source of
norms. Journal of Clinical and Experimental Neuropsychology, 33 (5):596-603, 2011
--Sternberg S, Wershof Schwartz A, Karunananthan S, Bergman H and Clarfield AM. The
Identification of Frailty: A Systematic Literature Review Journal of the American Geriatrics
Society, 59:2129–2138, 2011
--Arsenault-Lapierre G, Whitehead V, Belleville S, Massoud F, Bergman H, Chertkow H. Mild
Cognitive Impairment Subcategories Depend on the Source of Norms. Journal of Clinical and
Experimental Neuropsychology, 33 (5):596-603, 2011
Blostein, Mark
-- Granger et al for the ARISTOTLE Committees and Investigators*. Apixaban versus Warfarin
in Patients with Atrial Fibrillation New England Journal of Medicine 2011; 365:981-99, 2011*
local site investigator
--Goldfarb MJ, Blostein MD. Fondaparinux in Acute Heparin-Induced Thrombocytopenia - A
Case Series. Journal of Thrombosis and Hemostasis, 9:2501-3, 2011
-- D’Souza, PM, Blostein, MD. Report of a Case of Heyde's Syndrome Diagnosed by Abnormal
Closure Times Despite Normal Von Willebrand's Activity. Blood, Coagulation, and Fibrinolysis,
22:622-623, 2011
--Rasti M, Blostein, MD. Delayed immune mediated thrombocytopenia after re-exposure
to abciximab therapy. Canadian Journal of Cardiology, 27:869, 2011
-- Blostein MD, Rajotte I, Rao DP, Holcroft CA, Kahn SR. Elevated plasma gas6 levels are
associated with venous thromboembolic disease. J Thromb Thrombolysis.32:272-278, 2011
--Lemarié CA, Shbat L, Marchesi C, Angulo OJ, Deschênes ME, Blostein MD, Paradis P,
Schiffrin EL. Mthfr deficiency induces endothelial progenitor cell senescence via uncoupling of
eNOS and downregulation of SIRT1.Am J Physiol Heart Circ Physiol. 300:H745- , 2011
-- Coutu DL, Cuerquis J, El Ayoubi R, Forner KA, Roy R, François M, Griffith M, Lillicrap D,
Yousefi AM, Blostein MD, Galipeau J. Blostein, MD Hierarchical scaffold design for
mesenchymal stem cell-based gene therapy of hemophilia B.Biomaterials. 32(1):295-305, 2011
Chalifour, Lorraine
Sebag IA, Gillis MA, Calderone A, Kasneci A, Meilleur M, Haddad R, Noiles W, Patel B,
Chalifour LE. Sex hormone control of left ventricular structure/function: mechanistic insights
using echocardiography, expression, and DNA methylation analyses in adult mice. Am J Physiol
Heart Circ Physiol, 301:1706-15, 2011
Cohen, A
--Alzafiri R, Holcroft CA, Malolepszy P, Cohen A, Szilagyi A. Infliximab therapy for
moderately severe Crohn's disease and ulcerative colitis: a retrospective comparison over 6
years. Clin Exp Gastroenterol; 2011;4:9-17. Epub January 2011
Cohen, Robin
--*Mehta A, Cohen SR, Ezer H, Carnevale F, Ducharme F. Striving to respond to palliative care
patients’ pain at home: a puzzle for family caregivers.OncolNurs Forum. 38:E37-45, 2011
--Williams AM, Eby JA, Crooks VA, Stajduhar K, Giesbrecht M, Vuksan M, Cohen SR, Brazil
K, Allan D. Canada's Compassionate Care Benefit: Is it an adequate public health response to
addressing the issue of caregiver burden in end-of-life care? BMC Public Health.11:335, 2011
--Jones J, McPherson C, Zimmermann C, Rodin G, Cohen SR. Assessing agreement between
terminally ill cancer patients’ reports of their quality of life with family caregiver and palliative
care physician proxy ratings. J Pain Symptom Manage. 42:354-365, 2011
--Stajduhar K, Funk L, Cohen SR, Williams A, Bidgood D, Allan D, Norgrove L, Heyland D.
Bereaved family members’ assessments of the quality of EOL care: What is important? J Palliat
Care 27:261-269, 2011
Chertkow, Howard
--Sherwin BB, Chertkow H, Schipper H, Nasreddine Z. A randomized controlled trial of
estrogen treatment in men with mild cognitive impairment. Neurobiol Aging, 32:1808-1817,
2011
--Taler V, Kousaie S, Phillips NA, Chertkow H, Titone D. Generation of novel semantic
representations in aging and Alzheimer disease. Journal of Neurolinguistics, 24 (3):293-303,
2011
--Sinai M, Phillips NA, Chertkow H, Kabani NJ. Task switching performance reveals
heterogeneity amongst patients with mild cognitive impairment. Neuropsychology, 24 (6):757774, 2010
--De Boysson C, Belleville S, Phillips NA, Johns EK, Goupil D, Souchay C, Bouchard R,
Chertkow H. False recognition in Lewy-Body Disease and Frontotemporal Dementia. Brain and
Cognition, 75 (2): 111-118, 2011
--McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack Jr CR, Kawas CH, et al. The
diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute
on Aging and Alzheimer’s Association workgroup. Alzheimer’s & Dementia. 7(3):263-269,
2011
--Brunet J, Hudon C, Macoir J, Belleville S, Rousseau F, Bouchard RW, Verret L, Chertkow H,
Chayer C, Kergoat M-J, Joubert S. The relation between depressive symptoms and semantic
memory in amnestic mild cognitive impairment and in late-life depression. Journal of the
International Neuropsychological Society, 17:865-874, 2011
--Maes OC, Chertkow HM, Wang E, Schipper HM. Stress gene deregulation in Alzheimer
peripheral blood mononuclear cells. In: S. Basu. L. Wiklund (Eds.): Oxidative Stress in Applied
Basic Research and Clinical Practice: Studies on Experimental Models. Springer Science, New
York, 10: 251-263, 2011
Dascal, Andre
--Allard R, Dascal A, Camara B, Létourneau J, Valiquette L. Community-acquired Clostridium
difficile – associated diarrhea, Montreal 2005-2006 frequency estimates and their validity. Infect
Control Hosp Epidemiol. 32:1032-4, 2011 Epub 2011 Aug 10. PMID: 21931255
--Loo VG, Bourgault AM, Poirier L, Lamothe F, Michaud S, Turgeon N, Toye B, Beaudoin A,
Frost EH, Gilca R, Brassard P, Dendukuri N, Béliveau C, Oughton M, Brukner I, Dascal A
(senior author) . Host and pathogen factors for Clostridium difficile infection and colonization. N
Engl J Med. 365:18:1693-703, 2011 PMID: 22047560 [ also Correspondance: Loo VG,
Bourgault AM, Dascal A Reply to comments –submitted].
Eintracht, Dr. Shaun
--Zhang M, Robitaille L, Eintracht S, Hoffer L.J. Vitamin C provision improves mood in
acutely hospitalized patients, Nutrition 27:530-533, 2011
Eisenberg, Mark J.
--Kouz S, Kouz R, Schampaert E, Rinfret S, Tardif JC, Nguyen M, Eisenberg M, Harvey R,
Afilalo M, Lauzon C, Dery JP, Mansour S, Huynh T. Effectiveness and safety of glycoprotein
IIb/IIIa inhibitors in patients with myocardial infarction undergoing primary percutaneous
coronary intervention: A meta-analysis of observational studies. Int J Cardiol, 153:249-55, 2011
--*Shimony A, Filion KB, *Mottillo S, *Dourian T, Eisenberg MJ. Meta-analysis of usefulness
of D-dimer to diagnose acute aortic dissection. Am J Cardiol, 107:1227-34, 2011
--Eisenberg MJ, *Afilalo J, *Lawler PR, Abramovitch M, Richard H, Pilote L. Cancer risk
related to low-dose ionizing radiation from cardiac imaging in patients following acute
myocardial infarction. CMAJ, 183:430-6, 2011
--Pipe AL, Eisenberg MJ, Gupta A, Reid RD, Suskin NG, Stone JA. Canadian Cardiovascular
Society position statement on smoking cessation. Can J Cardiol, 27:132-7, 2011
--Roifman I, Beck PL, Anderson TJ, Eisenberg MJ, Genest J. Chronic inflammatory diseases
and cardiovascular risk: A systematic review. Can J Cardiol, 27:174-82, 2011
--Eisenberg MJ, *Atallah R, *Grandi S, *Windle SB, Berry EM. Legislative approaches to
tackling the obesity epidemic. CMAJ, 183:1496-500, 2011
--Kotowycz MA, Filion KB, Joza J, Dube D, Reynolds MR, Pilote L, Eisenberg MJ, Essebag V.
In-hospital management of atrial fibrillation: The CHADS(2) score predicts increased cost. Can J
Cardiol, 27:506-13, 2011
--*Shimony A, Eisenberg MJ, Rudski L, Schlesinger R, *Afilalo J, Joyal D, Dragatakis J,
Hirsch A, Boutet K, Fox BD, Langleben D. Prevalence and impact of coronary artery disease in
patients with pulmonary arterial hypertension. Am J Cardiol, 108:460-4, 2011
--*Mottillo S, *Sharma K, Eisenberg MJ. Therapeutic hypothermia in acute myocardial
infarction: A systematic review. Can J Cardiol, 27:555-61, 2011
--Jackevicius CA, Tom A, Essebag V, Eisenberg MJ, Rahme E, Tu JV, Humphries KH,
Behlouli H, Pilote L. Population-level incidence and risk factors for pulmonary toxicity
associated with amiodarone. Am J Cardiol, 108:705-10, 2011
--Tsadok MA, Jackevicius CA, Rahme E, Essebag V, Eisenberg MJ, Humphries KH, Tu JV,
Behlouli H, Joo J, Pilote L. Amiodarone-induced thyroid dysfunction: brand-name versus
generic formulations. CMAJ, 183:E817-23, 2011
--*Shimony A, Eisenberg MJ, Filion KB, Amit G. Beneficial effects of right ventricular nonapical vs. apical pacing: A systematic review and meta-analysis of randomized controlled trials.
Europace, Epub Jul 27, 2011
--*Shimony A, Joseph L, *Mottillo S, Eisenberg MJ. Coronary artery perforation during
percutaneous coronary intervention: A systematic review and meta-analysis. Can J Cardiol,
27:843-50, 2011
--*Filion KB, Abenhaim H, *Mottillo S, Joseph L, Gervais A, O’Loughlin J, Paradis G, Pihl R,
Pilote L, Rinfret S, Tremblay M, Eisenberg MJ. The effect of smoking cessation counselling in
pregnant women: A meta-analysis of randomised controlled trials. BJOG, 118:1422-8, 2011
--Afilalo J, Rasti M, Ohayon SM, *Shimony A, Eisenberg MJ. Off-pump versus on-pump
coronary artery bypass surgery: An updated meta-analysis and meta-regression of randomized
trials. Eur Heart J, Epub Oct 10, 2011
--*Lawler P, Filion KB, Eisenberg MJ. Efficacy of exercise-based cardiac rehabilitation postmyocardial infarction: A systematic review and meta-analysis of randomized controlled trials.
Am Heart J, 162:571-584. e2, 2011
--*Friedland SN, Eisenberg MJ, *Shimony A. Meta-analysis of randomized controlled trials of
intracoronary versus intravenous administration of glycoprotein IIb/IIIa inhibitors during
percutaneous coronary intervention for acute coronary syndrome. Am J Cardiol, 108:1244-51,
2011
--*Lawler PR, Afilalo J, Eisenberg MJ, Pilote L. Exposure to low-dose ionizing radiation from
cardiac imaging among patients with myocardial infarction. Am J Cardiol,Epub Sep 29, 2011
--*Reoch J, *Mottillo S, *Shimony A, Filion KB, Christou NV, Joseph L, Poirier P, Eisenberg
MJ. Safety of laparoscopic versus open bariatric surgery: A systematic review and metaanalysis. Arch Surg,146:1314-22, 2011
--*Shimony A, EisenbergMJ. Chapter 37: Practice guidelines in non-ST-segment elevation
acute coronary syndromes. In: 1001 Questions: An Interventional Cardiology Board Review
Mukherjee D, Cho L, Moliterno DJ, eds. Lippincott Williams & Wilkins, Philadelphia, PA, 2011
Ernst, Pierre
--Tan W C, Bourbeau J, Hernandez P, Chapman K, Cowie R, Fitzgerald M, Aaron S, Marciniuk
D, Maltais F, O'Donnell D, Goldstein R, Sin D, Chan-Yeung M, Manfreda J, Anthonisen N, Tate
R, Sears M, Siersted H, Becklake M, Ernst P, Bowie D, Sweet L, and Van Til L, Canadian
prediction equations of spirometric lung function for caucasian adults 20 to 90 years of age:
Results from the canadian obstructive lung disease (cold) study and the lung health canadian
environment (lhce) study. Can Respir J, 18:321-326, 2011
--O'Byrne P M, Pedersen S, Carlsson L G, Radner F, Thoren A, Peterson S, Ernst P and Suissa
S. Risks of pneumonia in patients with asthma taking inhaled corticosteroids. American journal
of respiratory and critical care medicine, 183:589-95, 2011
--Kawasumi Y, Ernst P, Abrahamowicz M and Tamblyn R, Association between physician
competence at licensure and the quality of asthma management among patients with out-ofcontrol asthma. Archives of internal medicine, 171:1292-4, 2011
--Kawasumi Y, Abrahamowicz M, Ernst P and Tamblyn R, Development and validation of a
predictive algorithm to identify adult asthmatics from medical services and pharmacy claims
databases. Health services research, 46:939-63, 2011
--Ernst P, Dell Aniello S, Mikaeloff Y and Suissa S, Risk of herpes zoster in patients prescribed
inhaled corticosteroids: A cohort study. BMC Pulm Med, 11:59, 2011
Filion, Kristian
--Wang H, Steffen LM, Jacobs DR, Zhou S, Berger AK, Blackburn H, Filion KB, Luepker RV.
Trends in cardiovascular risk factor levels in the Minnesota Heart Survey (1980-2002) as
compared with the National Health and Nutrition Examination Survey (1976-2002): a partial
explanation for Minnesota's low cardiovascular disease mortality? Am J Epidemiol, 173:526–
538, 2011
--Shimony A, Filion KB, Mottillo S, Dourian T, Eisenberg MJ. Meta-analysis of usefulness of
D-dimer to diagnose acute aortic dissection. Am J Cardiol, 107:1227-34, 2011
--Huxley RR, Filion KB, Konety S, Alonso A. Meta-analysis of cohort and case-control studies
of type-2 diabetes and the risk of atrial fibrillation. Am J Cardiol, 108:56-62, 2011
--Bogaty P, Filion KB, Brophy JM. Routine invasive management after fibrinolysis in patients
with ST-elevation myocardial infarction: a systematic review of randomized clinical trials.
BMC Cardiovasc Disord, 11:34, 2011
--Filion KB, Steffen L, Duval S, Jacobs DR Jr, Blackburn H, Luepker RV. Trends in smoking
among adults from 1980 to 2009: the Minnesota Heart Survey. Am J Public Health, Aug 18,
2011 [Epub ahead of print]
--Kotowycz MA, Filion KB, Joza J, Dube D, Reynolds MR, Pilote L, Eisenberg MJ, Essebag V.
In-hospital management of atrial fibrillation: the CHADS-2 score predicts increased cost. Can J
Cardiol, 27:506-513, 2011
--Thorogood A, Mottillo S, Shimony A, Filion KB, Joseph L, Genest J, Pilote L, Poirier P,
Schiffrin EL, Eisenberg MJ. Isolated aerobic exercise and weight loss: a systematic review and
meta-analysis of randomized controlled trials. Am J Med, 124:747-755, 2011
--Lawler P, Filion KB, Eisenberg MJ. Efficacy of exercise-based cardiac rehabilitation postmyocardial infarction: a systematic review and meta-analysis of randomized controlled trials.
Am Heart J, 162:571-584, 2011
--Filion KB, Steffen LM, Duval S, Jacobs DR Jr, Blackburn H, Luepker RV. Population-based
smoking trends in older adults: the Minnesota Heart Survey. J Am Geriatr Soc, 59:1970-1, 2011
--Filion KB, Joseph L, Boivin JF, Suissa S, Brophy JM. Thiazolidinediones and the risk of
incident congestive heart failure among patients with type 2 diabetes mellitus.
Pharmacoepidemiol Drug Saf, 20:785-96, 2011
--Reoch J, Mottillo S, Shimony A, Filion KB, Christou NV, Joseph L, Poirier P, Eisenberg MJ.
Safety of laparoscopic versus open bariatric surgery: a systematic review and meta-analysis of
randomized controlled trials. Arch Surg, 146:1314-22, 2011
--Filion KB, Abenhaim HA, Mottillo S, Joseph L, Gervais A, O’Loughlin J, Paradis G, Pihl R,
Pilote L, Rinfret S, Tremblay M, Eisenberg MJ. The effect of smoking cessation counseling in
pregnant women: a meta-analysis of randomized controlled trials. BJOG, 118:1422-8, 2011
--Lawler PR, Filion KB, Garfinkle M, Eisenberg MJ. Anemia, red blood cell transfusion and
mortality in patients with acute coronary syndromes: a meta-analysis and systematic review.
Circulation 124:A15887, 2011
--Filion KB, Sillah A, Luepker RV, Lakshminarayan K. Age-specific stroke trends from 1980 to
2000: the Minnesota Stroke Survey. Circulation 124:A13037, 2011
--Filion KB, Agarwal SK, Ballantyne CM, Hoogeveen RC, Huxley RR, Loehr LR, Nambi V,
Soliman EZ, Alonso A. High-sensitivity cardiac troponin T and the risk of incident atrial
fibrillation: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation 124:A8460,
2011
Foulkes, William
--Rio Frio T, Bahubeshi A, Kanellopoulou C, Hamel N, Niedziela M, Sabbaghian N, Pouchet C,
Gilbert L, O'Brien PK, Serfas K, Broderick P, Houlston RS, Lesueur F, Bonora E, Muljo S,
Schimke RN, Bouron-Dal Soglio D, Arseneau J, Schultz KA, Priest JR, Nguyen VH, Harach
HR, Livingston DM, Foulkes WD, Tischkowitz M. DICER1 mutations in familial multinodular
goiter with and without ovarian Sertoli-Leydig cell tumors. JAMA. 2011 Jan 5;305(1):68-77.
--Martinez-Marignac VL, Rodrigue A, Davidson D, Couillard M, Al-Moustafa AE, Abramovitz
M, Foulkes WD, Masson JY, Aloyz R The effect of a DNA repair gene on cellular invasiveness:
XRCC3 over-expression in breast cancer cells. PLoS One. 2011 Jan 24;6(1):e16394.
--Hamel N, Feng BJ, Foretova L, Stoppa-Lyonnet D, Narod SA, Imyanitov E, Sinilnikova O,
Tihomirova L, Lubinski J, Gronwald J, Gorski B, Hansen TV, Nielsen FC, Thomassen M,
Yannoukakos D, Konstantopoulou I, Zajac V, Ciernikova S, Couch FJ, Greenwood CM, Goldgar
DE, Foulkes WD. On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European
populations.Eur J Hum Genet.2011 Mar;19(3):300-6.
--Bernatsky S, Ramsey-Goldman R, Foulkes WD, Gordon C, Clarke AE. Breast, ovarian, and
endometrial malignancies in systemic lupus erythematosus: a meta-analysis. Br J Cancer. 2011
Apr 16;104(9):1478-81. Epub 2011 Apr 12.
--Shuen AY, Foulkes WD. Inherited mutations in breast cancer genes--risk and response.J
Mammary Gland Biol Neoplasia. 2011 Apr;16(1):3-15. Review.
--Metcalfe K, Gershman S, Lynch HT, Ghadirian P, Tung N, Kim-Sing C, Olopade OI,
Domchek S, McLennan J, Eisen A, Foulkes WD, Rosen B, Sun P, Narod SA. Predictors of
contralateral breast cancer in BRCA1 and BRCA2 mutation carriers. Br J Cancer. 2011 Apr
26;104(9):1384-92.
--Metcalfe K, Lynch HT, Ghadirian P, Tung N, Kim-Sing C, Olopade OI, Domchek S, Eisen A,
Foulkes WD, Rosen B, Vesprini D, Sun P, Narod SA. Risk of ipsilateral breast cancer in
BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat. 2011 May;127(1):287-96.
--Warner E, Hill K, Causer P, Plewes D, Jong R, Yaffe M, Foulkes WD, Ghadirian P, Lynch H,
Couch F, Wong J, Wright F, Sun P, Narod SA. Prospective study of breast cancer incidence in
women with a BRCA1 or BRCA2 mutation under surveillance with and without magnetic
resonance imaging. J ClinOncol. 2011 May 1;29(13):1664-9.
--Bordeleau L, Lipscombe L, Lubinski J, Ghadirian P, Foulkes WD, Neuhausen S, Ainsworth P,
Pollak M, Sun P, Narod SA; the Hereditary Breast Cancer Clinical Study Group. Diabetes and
breast cancer among women with BRCA1 and BRCA2 mutations, 117:1812-18,
2011/cncr.25595
--Baker K, Lachapelle J, Zlobec I, Bismar TA, Terracciano L, Foulkes WD. Prognostic
significance of CD8+ T lymphocytes in breast cancer depends upon both oestrogen receptor
status and histological grade. Histopathology. 2011 Jun;58(7):1107-16. doi: 10.1111/j.13652559.201103846.x.
--Lu L, Cancel-Tassin G, Valeri A, Cussenot O, Lange EM, Cooney KA, Farnham JM, Camp
NJ, Cannon-Albright LA, Tammela TL, Schleutker J, Hoegel J, Herkommer K, Maier C, Vogel
W, Wiklund F, Emanuelsson M, Grönberg H, Wiley KE, Isaacs SD, Walsh PC, Helfand BT, Kan
D, Catalona WJ, Stanford JL, Fitzgerald LM, Johanneson B, Deutsch K, McIntosh L, Ostrander
EA, Thibodeau SN, McDonnell SK, Hebbring S, Schaid DJ, Whittemore AS, Oakley-Girvan I,
Hsieh CL, Powell I, Bailey-Wilson JE, Cropp CD, Simpson C, Carpten JD, Seminara D, Zheng
SL, Xu J, Giles GG, Severi G, Hopper JL, English DR, Foulkes WD, Maehle L, Moller P,
Badzioch MD, Edwards S, Guy M, Eeles R, Easton D, Isaacs WB; International Consortium for
Prostate Cancer Genetics. Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan
of 762 prostate cancer families collected by the ICPCG. Prostate. 2011 Jul 11. doi:
10.1002/pros.21443. [Epub ahead of print]
--Allen C, Foulkes WD. Qualitative thematic analysis of consent forms used in cancer genome
sequencing. BMC Med Ethics. 2011 Jul 19;12(1):14.
--Vijai J, Kirchhoff T, Gallagher D, Hamel N, Guha S, Darvasi A, Lencz T, Foulkes WD, Offit
K, Klein R.Prostate cancer risk SNPs in the Ashkenazi. Br J Cancer. 2011 Aug 9. doi:
10.1038/bjc.2011307.
--Lubinski J, Huzarski T, Byrski T, Lynch HT, Cybulski C, Ghadirian P, Stawicka M, Foulkes
WD, Kilar E, Kim-Sing C, Neuhausen SL, Armel S, Gilchrist D, Sweet K, Gronwald J, Eisen A,
Gorski B, Sun P, Narod SA; The Hereditary Breast Cancer Clinical Study Group. The risk of
breast cancer in women with a BRCA1 mutation from north america and poland. Int J Cancer.
2011 Aug 10. doi: 10.1002/ijc.26369. [Epub ahead of print]
--Appleby-Tagoe JH, Foulkes WD, Palma L. Reading Between the Lines: A Comparison of
Responders and Non-responders to a Family History Questionnaire and Implications for Cancer
Genetic Counselling. J Genet Couns. 2011 Aug 16. [Epub ahead of print]
--Lachapelle J, Foulkes WD. Triple-negative and basal-like breast cancer: implications for
oncologists. CurrOncol. 2011 Aug;18(4):161-4.
--Nalwoga H, Arnes JB, Stefansson IM, Wabinga H, Foulkes WD, Akslen LA. Vascular
proliferation is increased in basal-like breast cancer. Breast Cancer Res Treat. 2011 Aug 28.
[Epub ahead of print]
--Arnes JB, Stefansson IM, Straume O, Baak JP, Lønning PE, Foulkes WD, Akslen LA.
Vascular proliferation is a prognostic factor in breast cancer. Breast Cancer Res Treat. 2011 Sep
27. [Epub ahead of print]
--Cote S, Arcand SL, Royer R, Nolet S, Mes-Masson AM, Ghadirian P, Foulkes WD,
Tischkowitz M, Narod SA, Provencher D, Tonin PN. The BRCA2 c.9004G>A (E2003K) variant
is likely pathogenic and recurs in breast and/or ovarian cancer families of French Canadian
descent. Breast Cancer Res Treat. 131(1):333-40. Epub 2011 Sep 27.
--Osher DJ, Kushner YB, Arseneau J, Foulkes WD.Melphalan as a treatment for BRCA-related
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study. Critical Reviews in Oncology/Hematology, 78:138–149, 2011
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Ponka, Prem
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Richard, Stephane
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Richards, J. Brent
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Schiffrin, Ernesto L.
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color-Doppler data. Medical Image Analysis, 15:577-88, 2011
Suissa, Samy
–Gonzalez AV, Suissa S, Ernst P. Gender differences in survival following hospitalisation for
COPD. Thorax 66:38-42, 2011
--Suissa S, Dell’Aniello S, Vahey S, Renoux C. Time-window bias in case-control studies:
statins and lung cancer. Epidemiology, 22:228-231, 2011
--Schneider-Lindner V, Quach C, Hanley JA, Suissa S. Secular trends of antibacterial
prescribing in UK paediatric primary care. J AntimicrobChemother, 66:424-433, 2011
--Brassard P, Suissa S, Kezouh A, Ernst P. Inhaled corticosteroids and risk of tuberculosis in
patients with respiratory diseases.Am J RespirCrit Care Med, 183:675-678, 2011
Azoulay L, Dell’Aniello S, Huiart L, du Fort GG, Suissa S. Concurrent use of tamoxifen with
CYP2D6 inhibitors and the risk of breast cancer recurrence. Breast Cancer Res Treat, 126:695703, 2011
--Huiart L, Dell’Aniello S, Suissa S. Use of tamoxifen and aromatase inhibitors in a large
population-based cohort of women with breast cancer. Br J Cancer, 104:1558-1663, 2011
--Suissa S, Ernst P. Mega trials in COPD – clinical data analysis and design issues. Pneumonol
Alergol Pol, 79:277-231, 2011
--Dixon WG, Kezouh A, Bernatsky S, Suissa S. The influence of systemic glucocorticoid
therapy upon the risk of non-serious infection in older patients with rheumatoid arthritis: a
nested case-control study. Ann Rheum Dis, 70:956-960, 2011
--Renoux C, Suissa S. Hormone therapy administration in postmenopausal women and risk of
stroke.Womens Health (LondEngl), 2011 May, 7:355-361, 2011
--Suissa S, Azoulay L, Dell’Aniello S, Evans M, Vora J, Pollak M. Long-term effects of insulin
glargine on the risk of breast cancer. Diabetologia, 54:2254-2262, 2011
--Azoulay L, Yin H, Benayoun S, Boivin JF, Suissa S. Androgen Deprivation Therapy and the
Risk of Stroke and Transient Ischemic Attacks in Patients with Prostate
Cancer.Pharmacoepidemiol Drug Saf, 20:S130-S131, 2011
--Duijnhoven R, Dell’Aniello S, Renoux C, Tagalakis V, Knol M, Klungel O, Suissa S. Effect of
Simultaneous Use of Oestrogens and Statins on the Risk for Venous Thromboembolism in PostMenopausal Women. Pharmacoepidemiol Drug Saf, 20:S131, 2011
--Suissa S, Henry D. The Establishment of the Canadian Network for Observational Drug Effect
Studies (CNODES). Pharmacoepidemiol Drug Saf, 20:S168, 2011
--Dixon WG, Suissa S, Hudson M. The association between systemic glucocorticoid therapy and
the risk of infection in patients with rheumatoid arthritis: systematic review and meta-analyses.
Arthritis Res Ther, 13:R139, 2011
--Azoulay L, Yin H, Renoux C, Suissa S. The use of atypical antipsychotics and the risk of
breast cancer. Breast Cancer Res Treat,129(2):541-548, 2011
--Azoulay L, Yin H, Benayoun S, Renoux C, Boivin JF, Suissa S. Androgen-deprivation therapy
and the risk of stroke in patients with prostate cancer.EurUrol, 60(6):1244-1250, 2011
--Schneider-Lindner V, Quach C, Hanley JA, Suissa S. Antibacterial Drugs and the Risk of
Community-Associated Methicillin-Resistant Staphylococcus aureus in Children. Arch Pediatr
Adolesc Med, 20:785-796, 2011
--Simon T, Azoulay L, Rosenman M, Ewen E, Kawabata H, Suissa S. How well do recent
studies of AF patients reflect the real world AF patient? Stroke, 42:e252, 2011
Szilagyi, Andrew
--Marton A, Xue X, Szilagyi A. Meta-analysis: the diagnostic accuracy of lactose breath
hydrogen or lactose tolerance tests for predicting the North European lactase polymorphism
C/T-13910. Aliment Pharmacol Therap, 2011 Dec 28. doi:10.1111/j.1365-2036.201104962.x.
[Epub ahead of print]
--Alharbi A, Almadi M, Szilagyi A. An Unusual Cause of Upper Gastrointestinal Bleeding.
Gastroenterology. 2011 Dec 19 [Epub ahead of print] PMID:22192427
--Szilagyi A, Leighton H, Burstein B, Shrier I. Significant positive correlation between sunshine
and lactase nonpersistence in Europe may implicate both in similarly altering risks for some
diseases. Nutrition Cancer, 63:991-9, 2011
--Szilagyi A. Lactase Phenotype and Relationships to Diseases. Advances in Genetics Research,
Volume 6, Nova Science Publishers Inc, New York, Editor; Kevin V Urbano. 287-308, 2011
ISBN: 978-1-61209-793-0.
Tagalakis, Vicky
--Dayan N, Tagalakis V, Holcroft C. The risk of venous thrombosis, including cerebral vein
thrombosis among women with thrombophilia and oral contraceptive use: a meta-analysis,
Clinical and Applied Thrombosis/Hemostasis, 1-12, 2011
--Tagalakis V, Kahn SR. Determining the test characteristics of diagnostic codes for the
diagnosis of venous thromboembolism in a medical service claims database, Pharmacoepidemiology and Drug Safety, 20:304-307, 2011
--Routhier N, Tagalakis V. VTE prophylaxis, British Medical Journal Point-of-Care, 2011;
available at: https://online.epocrates.com/u/29111087/VTE+prophylaxis
--Tagalakis V. Superficial thrombophlebitis, British Medical Journal Point-of-Care, 2011;
available at: https://online.epocrates.com/u/2911335/Superficial+thrombophlebitis
Therrien, Judith
--Beauchesne LM, Therrien J, Alvarez N, Bergin L, Burggraf G, Chetaille P, Gordon E, Kells
C, Kiess M, Mercier LA, Oechslin EN, Stein J, Tam JW, Taylor D, Williams A, Marelli A.
Status of adult congenital heart disease clinics in Canada: a survey on infrastructure, resources
and clinical volumes. IJC 2011
--Do DH, Therrien J, Marelli A, Martucci G, Sebag I. Right atrial size relates to invasive
markers of chronic diastolic dysfunction in an adult population with congenital heart disease.
Echocardiography, 28:109-16, 2011
--Lowe B, Therrien J, Martucci G, Marelli A. Diagnosis of pulmonary hypertension in the
congenital heart disease adult population: impact on outcome. J Am Coll Cardiol, 2010-2011
58:538-46, 2011
--Afilalo J, Therrien J, Pilote L, Ionescu-Ittu R, Martucci G, Marelli AJ. Geriatric congenital
heart disease:burden of disease and predictors of mortality. J Am Coll Cardiol, 58:1509-15, 2011
--Bouchardy J, Marelli A, Martucci G, Therrien J. Mirror Image Atrial Dilatation in Adult
Patients with Congenital Heart Disease and Atrial Fibrillation. Accepted Int J Cardio 2011
--Redington A, Smallhorn J, Therrien J, Webb GD, Chapter 65 Congenital Heart Disease,
Braunwald, 9th Ed. 2010-2011
Thombs, Brett
-- Thombs BD, Jewett LR, Assassi S, Baron M, Bartlett S, Costa Maia A, El-Baalbaki G, Furst
D, Gottesman K, Haythornthwaite JA, Hudson M, Impens A, Korner A, Leite C, Mayes MD,
Malcarne VL, Motivala SJ, Mouthon L, Nielson WR, Plante D, Poiraudeau S, Poole JL, Pope J,
Sauve M, Steele RJ, Suarez-Almazor ME, Taillefer S, van den Ende C, Arthurs E, Bassel M,
Delisle V, Milette K, Leavens A, Razykov I, Khanna D. New Directions for Patient-Centered
Care in Scleroderma: The Scleroderma Patient-Centered Intervention Network (SPIN). Clin Exp
Rheumatol 2011 Dec 21. [Epub ahead of print]
Tischkowitz, Marc
–Ben Amor IM, Edouard T, Glorieux FH, Chabot G, Tischkowitz M, Roschger P, Klaushofer K,
Rauch F.J Bone Miner Res. Low bone mass and high material bone density in two patients with
Loeys-Dietz syndrome caused by transforming growth factor receptor 2 mutations. 2011 Nov 16.
doi: 10.1002/jbmr.1470 (early online publication).
--Gelmon KA, Tischkowitz M, Mackay H, Swenerton K, Robidoux A, Tonkin K, Hirte H,
Huntsman D, Clemons M, Gilks B, Yerushalmi R, Macpherson E, Carmichael J, Oza A.
Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma
or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study.
Lancet Oncol. 12:852-61, 2011
--Villeneuve H, Tremblay S, Galiatsatos P, Hamel N, Guertin L, Morency R, Tischkowitz M.
Familial Cancer. 2011 Dec;10(4):691-4. Acinic cell carcinoma of the retromolartrigone region:
expanding the tumor phenotype in Cowden syndrome?
--Antoniou AC, Kartsonaki C, Sinilnikova OM, Soucy P, McGuffog L, Healey S, Lee A,
Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Cattaneo E, Barile M, Pensotti V, Pasini B,
Dolcetti R, Giannini G, Putignano AL, Varesco L, Radice P, Mai PL, Greene MH, Andrulis IL,
Glendon G, Ozcelik H; Ontario Cancer Genetics Network, Thomassen M, Gerdes AM, Kruse
TA, Jensen UB, Crüger DG, Caligo MA, Laitman Y, Milgrom R, Kaufman B, Paluch-Shimon S,
Friedman E, Loman N, Harbst K, Lindblom A, Arver B, Ehrencrona H, Melin B; SWE-BRCA,
Nathanson KL, Domchek SM, Rebbeck T, Jakubowska A, Lubinski J, Gronwald J, Huzarski T,
Byrski T, Cybulski C, Gorski B, Osorio A, Cajal TR, Fostira F, Andrés R, Benitez J, Hamann U,
Hogervorst FB, Rookus MA, Hooning MJ, Nelen MR, van der Luijt RB, van Os TA, van
Asperen CJ, Devilee P, Meijers-Heijboer HE, Gómez Garcia EB; HEBON, Peock S, Cook M,
Frost D, Platte R, Leyland J, Evans DG, Lalloo F, Eeles R, Izatt L, Adlard J, Davidson R, Eccles
D, Ong KR, Cook J, Douglas F, Paterson J, Kennedy MJ, Miedzybrodzka Z; EMBRACE,
Godwin A, Stoppa-Lyonnet D, Buecher B, Belotti M, Tirapo C, Mazoyer S, Barjhoux L, Lasset
C, Leroux D, Faivre L, Bronner M, Prieur F, Nogues C, Rouleau E, Pujol P, Coupier I, Frénay
M; GEMO Study Collaborators, Hopper JL, Daly MB, Terry MB, John EM, Buys SS, Yassin Y,
Miron A, Goldgar D; Breast Cancer Family Registry, Singer CF, Tea MK, Pfeiler G, Dressler
AC, Hansen TV, Jønson L, Ejlertsen B, Barkardottir RB, Kirchhoff T, Offit K, Piedmonte M,
Rodriguez G, Small L, Boggess J, Blank S, Basil J, Azodi M, Toland AE, Montagna M,
Tognazzo S, Agata S, Imyanitov E, Janavicius R, Lazaro C, Blanco I, Pharoah PD, Sucheston L,
Karlan BY, Walsh CS, Olah E, Bozsik A, Teo SH, Seldon JL, Beattie MS, van Rensburg EJ,
Sluiter MD, Diez O, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Ruehl I, VaronMateeva R, Kast K, Deissler H, Niederacher D, Arnold N, Gadzicki D, Schönbuchner I, Caldes
T, de la Hoya M, Nevanlinna H, Aittomäki K, Dumont M, Chiquette J, Tischkowitz M, Chen X,
Beesley J, Spurdle AB; kConFab investigators, Neuhausen SL, Ding YC, Fredericksen Z, Wang
X, Pankratz VS, Couch F, Simard J, Easton DF, Chenevix-Trench G; on behalf of CIMBA.
Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and
BRCA2 mutation carriers. Hum Mol Genet. 20(16):3304-3321, 2011
--Sabbaghian N, Kyle R, Hao A, Hogg D, Tischkowitz M. Mutation analysis of the PALB2
cancer predisposition gene in familial melanoma. Familial Cancer, 10: 2:315-317, 2011
--Mitra AV, Bancroft EK, Barbachano Y, Page EC, Foster CS, Jameson C, Mitchell G,
Lindeman GJ, Stapleton A, Suthers G, Evans DG, Cruger D, Blanco I, Mercer C, Kirk J, Maehle
L, Hodgson S, Walker L, Izatt L, Douglas F, Tucker K, Dorkins H, Clowes V, Male A,
Donaldson A, Brewer C, Doherty R, Bulman B, Osther PJ, Salinas M, Eccles D, Axcrona K,
Jobson I, Newcombe B, Cybulski C, Rubinstein WS, Buys S Townshend S, Friedman E,
Domchek S, Ramon y Cajal T, Spigelman A, Teo SH, Nicolai N, Aaronson N, Ardern-Jones A,
Bangma C, Dearnaley D Eyfjord J, Falconer A, Grönberg H, Hamdy F, Johannsson O, Khoo V,
Kote-Jarai Z, Lilja H, Lubinski J, Melia J, Moynihan C, Peock S, Rennert G, Schröder F, Sibley
P, Suri M, Wilson P, Bignon YJ, Strom S, Tischkowitz M, Liljegren A, IlencikovaD,Abele A,
Kyriacou K; van Asperen C, Kiemeney L, The IMPACT Study Collaborators, Easton DF, and
Eeles R. Targeted Prostate Cancer Screening in Men with Mutations in BRCA1 and BRCA2
Detects Aggressive Prostate Cancer: Results from the IMPACT Pilot Study. British Journal of
Urology,107:28-39, 2011
--Karalis A, Tischkowitz M, Millington WM. Dermatological Manifestations of Inherited
Cancer Syndromes in Children. Br J Dermatol. 164:245-56, 2011
--Tischkowitz M, Winqvist R. J Using mouse models to investigate the biological and
physiological
consequences of defects in the Fanconianaemia/breast cancer DNA repair
signalling pathway. Pathol. 224:301-5, 2011
Zaharatos, Gerry J.
--Wainberg MA, Zaharatos GJ, Brenner BG. Development of antiretroviral drug resistance.
New England Journal of Medicine, 365:637-46, August 2011
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