Schedule of Events - Pittsburg State Gorillas

Miracor Medical Systems GmbH
There is No Better Way to Cure a Broken HeartTM
10th MedTech Investing Europe Conference
Lausanne, Switzerland
February 19th, 2010
www.miracormedical.com
Coronary Stents Open Arteries...
Coronary Flow in Heart Attack
Patients after Stents
92.4%
Poor 0/1
Medium 2
Excellent 3
2.90%
2.90%
Stone et al. JACC 2002
Coronary Stents Open Arteries...
There is No Better Way to Cure a Broken HeartTM
... But Not Microcirculation
Microcirculation
30.20%
27.90%
Poor 0/1
Medium 2
Excellent 3
41.90%
Stone et al. JACC 2002
.... But Not Microcirculation
There is No Better Way to Cure a Broken HeartTM
18,3% Mortality @ 12 Months
Stone et al. JACC 2002
18,3% Mortality @ 12 Months
There is No Better Way to Cure a Broken HeartTM
Market Research Europe & US
21of 24 (88%) Interventional Cardiologists Say
They Need a Technology to Improve
Microcirculation in Critical Heart Attack Patients
Market Growth
Angioplasty CAGR = 7.2% (2002-2009).
Market Segment
Worldwide 3.0M angioplasties in 2009.
BMO Capital Markets “2010 Medtech Outlook”, 01/10
Miracor Market Research 2009
Market Research Europe & US
There is No Better Way to Cure a Broken HeartTM
Experimental Theory
Myocardial infarction
without reperfusion
Myocardial infarction
with reperfusion
Myocardial infarction
with reperfusion and
cardioprotection
Murry et al., Circulation 1986
Yellon & Husenloy, NEJM 2007
Experimental Theory
There is No Better Way to Cure a Broken HeartTM
Miracor Animation: www.miracormedical.com/animation
Redistribution of Flow
Redistribution of Flow
There is No Better Way to Cure a Broken HeartTM
Early Clinical Data Exist
Reduction on Major Cardiovascular Events & Re-infarction
in Patients Undergoing Thrombolytics
86% reduction of the risk to
suffer MACE in patients
treated with PICSOTM
compared to control patients.
96% reduction of the risk for
re-infarction in patients
treated with PICSOTM
compared to control patients.
Mohl et al. Circ J 2008
Early Clinical Data Exist
There is No Better Way to Cure a Broken HeartTM
Milestone Achievements
Achieved Milestones
May 2008
Oct 2008
Attracts €6M Kick-off R&D
in VC
Project
Oct 2009
Aug 2009
Preclinical First Human
Cases
Trial n=12
(Safety Trial)
Feb 2010
EN ISO
13485
Future Milestones
Q2/10
European CEmark Trial
Milestone Achievements
Q4/10
Complete CEmark Trial
Q2/11
Next Financing
Round
There is No Better Way to Cure a Broken HeartTM
Partners
FINANCING
CUSTOMERS / KOLs
REGULATORY
Prof. Werner Mohl [A]
Prof. Norbert Frey [D]
SUPPORT
Prof. Patrick Serruys [NL]
MARKET RESEARCH
Prof. Otto Hess [CH]
TECHNOLOGY
Prof. Jens Kastrup [DK]
Dr. Lars Åberge [N]
IP/PATENTS
Dr. Beat Walpoth [CH]
ARTORG
Prof. Gittenberger de Groot [NL]
Partners
There is No Better Way to Cure a Broken HeartTM
Solid Patent Portfolio
Name
PICSO 2
PICSO 3
PICSO 4
PICSO 5
PICSO 6
Solid Patent Portfolio
Descript ion
Country and Patent No.
AT 410396
Status
G ranted
Devic e f or inter m ittent
oc c lus ion of the c oronary
s inus
USA 7331922
G ranted
J apan 4106019
G ranted
EP 02759855.6
Pending
AT 500676
G ranted
EP 05747274.8
Pending
USA (Appl. No. 11/597 834)
Pending
J P (Appl. No. 2007 - 526101)
Pending
AT 500688
G ranted
EP 05750183.5
Pending
USA (Appl. No. 11/629 401)
Pending
AT 503787
G ranted
PICSO with detailed
des c r iptions of how to
c ontrol the inf late/def late
c yc le
PICSO with f ur ther details
on how to c ontr ol the balloon
PICSO with a s ec ond
puls ating balloon f or c ardiac
s ur ger y
Im plantable PICSO
PCT (Appl. No.
PCT /AT 2007/000543)
Aus tria (Appl. No. A1856/2008)
Filed on 27/11/08
USA (Appl. No. 12/317 474)
Filed on 22/12/08
There is No Better Way to Cure a Broken HeartTM
Experienced Management Team
Oliver A. Kohr,
CTO
20 years medtech
R&D: Stanford,
Hannover, IontoComed, Klaschka
and Schaerer
Medical
Olaf Nitz, QA&RA
6 years medtech
background:
Swisstronics and
Synthes handling Class
III medical devices
Experienced Management Team
Jon H. Hoem, CEO
20 years medtech
Vingmed Sound (GE),
Medi-Stim (Medtronic)
and AtriCure
Martin Stapf, CFO
22 years
experience financial
services sector:
Global Refund
There is No Better Way to Cure a Broken HeartTM
Thank You!
Miracor Medical Systems GmbH
[email protected]
www.miracormedical.com
Thank You!
There is No Better Way to Cure a Broken HeartTM
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